Key differences between the Samsung A-series and S-series tablets?

[clsven]

When I look at the Samsung tablet models, there are two series:
A (e.g. Samsung Galaxy Tab A9+ 128GB 5G)

and

S (e.g. Samsung Galaxy Tab S9 FE+ 128GB 5G)

Are there any fundamental differences that justify a price that is twice (!) as high on average?

It can't be a faster processor alone.